મન રાખવું, ને ઝેર ચાખવું બરાબર છે.

mana rākhavuṁ, nē jhēra cākhavuṁ barābara chē.

Literally: Pleasing someone's mind and tasting poison are equal.
What it means: Trying to please everyone or maintaining a false relationship is as painful and destructive as consuming poison.

Also said as

ગુજરાતી કહેવતસંગ્રહ (Gujarati Kahevat Sangrah) (1923) · read from the scan by machine — the Gujarati itself is unchecked · English is machine-made and nobody has checked it yet

Heard it differently, or know we've got the sense wrong? Tell us — that is exactly the kind of correction this needs.