છેલ્લું ઓસડ છાસ.

chēlluṁ ōsaḍa chāsa.

Literally: The final medicine is buttermilk.
What it means: When all expensive or complex remedies fail, simple and basic home remedies are the last resort.

Also said as

ગુજરાતી કહેવતસંગ્રહ (Gujarati Kahevat Sangrah) (1923) · read from the scan by machine — the Gujarati itself is unchecked · English is machine-made and nobody has checked it yet

Heard it differently, or know we've got the sense wrong? Tell us — that is exactly the kind of correction this needs.